We examined the role of selenium in treating myocardial infarction (MI), a major cause of death worldwide that can lead to serious heart problems. The study focused on how this antioxidant works across different phases of a heart attack, where harmful reactive oxygen species (ROS) play a significant role in worsening the condition.
Our findings highlighted a new approach using selenium-embedded nanoparticles, which are specially designed to act as antioxidants at various stages of MI. This innovative method allows for selective ROS elimination when it's most needed, leading to impressive recovery outcomes for the heart.
Throughout the research, it became clear that these nanoparticles help protect vital functions in heart cells by reducing cell death, inflammation, and scar tissue, while also encouraging new blood vessel growth. Overall, this self-sustaining antioxidant strategy shows great potential, not just for treating heart attacks but also inspiring therapies for other ischemic conditions.
Read More
9
Selenium nanoparticles aid heart recovery
Mitigation of ischemia/reperfusion injury via selenium nanoparticles: Suppression of STAT1 to inhibit cardiomyocyte oxidative stress and inflammation.
We investigated the potential of spherical selenium nanoparticles (SeNPs) to reduce the harmful effects of ischemia/reperfusion injury (I/RI) that often occurs after a heart attack. The study involved intravenous injections of these nanoparticles, which showcased impressive antioxidant and anti-inflammatory properties.
Our findings revealed that SeNPs effectively disrupted the harmful cycle of oxidative stress and inflammation associated with heart damage. They helped protect the heart cells by keeping mitochondrial functions intact and reducing programmed cell death, also known as apoptosis. Furthermore, SeNPs managed to lessen the invasion of inflammatory cells and reduce the release of harmful mediators during I/RI.
In practical terms, when tested in vivo, the selenium nanoparticles significantly improved heart function while reducing both cell death and tissue scarring. This indicates that these nanoparticles could offer a promising new approach to enhance treatments following heart attacks, specifically by focusing on the key pathway of STAT1, which plays a crucial role in mediating injury and inflammation.
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2
Vitamin E links to heart risks
Circulating Vitamin E Levels and Risk of Coronary Artery Disease and Myocardial Infarction: A Mendelian Randomization Study.
We explored the relationship between vitamin E and heart attack risk through a two-sample mendelian randomization study. Using genetic variations from nearly 8,000 individuals of European descent, we dug into whether higher levels of vitamin E could protect against coronary artery disease (CAD) and myocardial infarction (MI).
Contrary to some previous beliefs about its benefits, our results suggested that increased vitamin E levels were actually associated with a higher risk of both CAD and MI. This means it's time to rethink the safety and effectiveness of vitamin E supplements for heart health.
Read More
Most Useful Reviews
9
Improved energy levels
4 people found this helpful
The complex is effective! I began taking it on the advice of a nutritionist to restore my thyroid function, addressing fatigue, muscle weakness, and heart issues. Almost immediately, I felt better; my energy increased, hair loss decreased, and my heartbeat was more stable. I recommend this essential vitamin for optimal body performance. Please like if you find this helpful.
Read More
9
Improved heart function
1 people found this helpful
Selenium is vital for health; it aids iron and iodine absorption, boosts immunity, and lowers heart attack risks while improving blood pressure. I took it regularly and felt more energetic and rejuvenated. The capsules are easy to take in the morning before meals. Please like if this helped!
Read More
9
Avoided hormone therapy
1 people found this helpful
I avoided hormone therapy thanks to this product. I felt constantly tired with heart arrhythmia last year, but this selenium product has been life-changing. I definitely don't want to go without it.
We examined the role of selenium in treating myocardial infarction (MI), a major cause of death worldwide that can lead to serious heart problems. The study focused on how this antioxidant works across different phases of a heart attack, where harmful reactive oxygen species (ROS) play a significant role in worsening the condition.
Our findings highlighted a new approach using selenium-embedded nanoparticles, which are specially designed to act as antioxidants at various stages of MI. This innovative method allows for selective ROS elimination when it's most needed, leading to impressive recovery outcomes for the heart.
Throughout the research, it became clear that these nanoparticles help protect vital functions in heart cells by reducing cell death, inflammation, and scar tissue, while also encouraging new blood vessel growth. Overall, this self-sustaining antioxidant strategy shows great potential, not just for treating heart attacks but also inspiring therapies for other ischemic conditions.
Read More
9
Selenium nanoparticles aid heart recovery
Mitigation of ischemia/reperfusion injury via selenium nanoparticles: Suppression of STAT1 to inhibit cardiomyocyte oxidative stress and inflammation.
We investigated the potential of spherical selenium nanoparticles (SeNPs) to reduce the harmful effects of ischemia/reperfusion injury (I/RI) that often occurs after a heart attack. The study involved intravenous injections of these nanoparticles, which showcased impressive antioxidant and anti-inflammatory properties.
Our findings revealed that SeNPs effectively disrupted the harmful cycle of oxidative stress and inflammation associated with heart damage. They helped protect the heart cells by keeping mitochondrial functions intact and reducing programmed cell death, also known as apoptosis. Furthermore, SeNPs managed to lessen the invasion of inflammatory cells and reduce the release of harmful mediators during I/RI.
In practical terms, when tested in vivo, the selenium nanoparticles significantly improved heart function while reducing both cell death and tissue scarring. This indicates that these nanoparticles could offer a promising new approach to enhance treatments following heart attacks, specifically by focusing on the key pathway of STAT1, which plays a crucial role in mediating injury and inflammation.
Read More
9
Selenium's potential in cardiac recovery
Facile fabrication of biocompatible injectable blended polymeric hydrogel with bioactive nanoformulation to improving cardiac tissue regeneration efficiency after myocardial infarction for nursing care potential applications.
We investigated how selenium, specifically in the form of selenium nanoparticles (Se NPs), can play a role in recovering from heart attacks. Our study focused on developing a unique hydrogel that combines Se NPs with a polymer base to improve cardiac repair after acute myocardial infarction (MI).
We explored the effects of the Se NPs on human heart cells and conducted experiments on mice models. The results were promising; the hearts of the treated mice showed a significant improvement with the left ventricular wall thickness increasing from a mere 235.6 micrometers to an impressive 390 micrometers.
Not only did these treatments help thicken the heart walls, but we also saw a remarkable reduction in scar thickness and infarct size when compared to control groups. This suggests that our selenium-infused hydrogel could be a valuable solution to promote heart healing post-MI, paving the way for potentially advanced treatments in the future.
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9
Gold nanocages help heart recovery
L-Arginine-Loaded Gold Nanocages Ameliorate Myocardial Ischemia/Reperfusion Injury by Promoting Nitric Oxide Production and Maintaining Mitochondrial Function.
We explored the potential of a novel treatment involving L-arginine-loaded gold nanocages designed to help with heart attack recovery. This innovative approach aims to tackle the problem of myocardial ischemia/reperfusion injury, a condition that can cause additional damage to the heart after blood flow is restored post-heart attack.
The gold nanocages in this study were enhanced with selenium and targeted towards heart cells, allowing for better absorption and effectiveness. Our tests showed that this treatment reduced cell damage and improved cell health during oxygen and glucose deprivation, which is crucial during heart attacks.
Furthermore, we observed that this treatment can help maintain mitochondrial function, leading to better energy production in heart cells. By preventing harmful oxidative reactions, it helps preserve nitric oxide, a vital molecule that supports heart health.
Ultimately, the results indicated that this approach could improve overall heart function and reduce cell death in heart tissue. The findings are promising and suggest a new pathway for effective heart attack treatments while ensuring safe and biocompatible use in living organisms.
Read More
9
Selenium treatment for heart attack
Injectable selenium-containing polymeric hydrogel formulation for effective treatment of myocardial infarction.
We explored an innovative approach to treating heart attacks, specifically looking at how selenium can make a difference. Our study focused on a special injectable hydrogel made from a combination of selenium, polypropylene glycol, and polyethylene glycol. The goal was to see if this formulation could help reduce inflammation and fibrosis after a myocardial infarction (heart attack).
We conducted our research on a mouse model of myocardial infarction, observing the effects of our selenium-containing hydrogel. The results were promising—our formulation demonstrated the ability to promote recovery in heart function. Through various tests, including enzyme-linked immunosorbent assays and tissue analysis, we confirmed that the gel effectively inhibits harmful inflammation and fibrosis that often occur after a heart attack.
Overall, this work highlights the potential of selenium as a beneficial component in therapies for heart attacks and possibly other inflammatory conditions. Our findings suggest that a selenium-infused polymeric hydrogel could be an effective strategy for improving heart health in the aftermath of a myocardial infarction.
The complex is effective! I began taking it on the advice of a nutritionist to restore my thyroid function, addressing fatigue, muscle weakness, and heart issues. Almost immediately, I felt better; my energy increased, hair loss decreased, and my heartbeat was more stable. I recommend this essential vitamin for optimal body performance. Please like if you find this helpful.
Read More
9
Improved heart function
1 people found this helpful
Selenium is vital for health; it aids iron and iodine absorption, boosts immunity, and lowers heart attack risks while improving blood pressure. I took it regularly and felt more energetic and rejuvenated. The capsules are easy to take in the morning before meals. Please like if this helped!
Read More
9
Avoided hormone therapy
1 people found this helpful
I avoided hormone therapy thanks to this product. I felt constantly tired with heart arrhythmia last year, but this selenium product has been life-changing. I definitely don't want to go without it.
Read More
7.5
Promotes cardiovascular health
1 people found this helpful
Excellent! Selenium-rich foods enhance cardiovascular health, acting as an anti-inflammatory and improving blood flow. Studies suggest selenium reduces the risk of heart disease and combats atherosclerosis.
Read More
7.5
Enhanced physical activity
1 people found this helpful
I found significant benefits from this supplement. It boosted my physical activity and decreased fatigue due to thyroid issues, contributing to better overall health and heart function.
A heart attack, also known as myocardial infarction, occurs when blood flow to a part of the heart is blocked, often by a blood clot. This interruption can damage or destroy part of the heart muscle, leading to serious health complications or death if not treated promptly. Common symptoms include chest pain, shortness of breath, nausea, and lightheadedness. Risk factors include high blood pressure, high cholesterol, smoking, diabetes, and a sedentary lifestyle.
Preventing a heart attack largely revolves around maintaining a heart-healthy lifestyle. Regular exercise, a balanced diet rich in fruits, vegetables, whole grains, and lean proteins, along with managing stress, can significantly lower the risk. Furthermore, understanding your personal risk factors and engaging with healthcare professionals for regular check-ups can be crucial in both prevention and early detection. If you suspect someone is having a heart attack, it's important to call emergency services immediately, as timely treatment is vital for survival and recovery.
Selenium is a powerful and widely used open-source tool designed for automating web applications for testing purposes. It enables developers and testers to write code in various programming languages such as Java, Python, C#, and Ruby to simulate user interactions with a web browser. Selenium's flexibility allows users to create complex test scenarios that mimic real-world user behaviors, making it an essential tool for ensuring web application functionality and performance.
In addition to its core functionalities, Selenium consists of several components, including Selenium WebDriver for automating browsers, Selenium Grid for running tests across multiple machines and environments in parallel, and Selenium IDE for record-and-playback test creation. Its compatibility with multiple browser types—such as Chrome, Firefox, Safari, and Edge—makes it a versatile choice for automated testing, catering to a wide range of projects and team needs. For anyone involved in web development or quality assurance, understanding and utilizing Selenium can significantly improve testing efficiency and reliability.
Based on user reviews, the time it takes to see results from taking selenium supplements for heart health varies, but many report feeling positive effects relatively quickly. Some users, such as the reviewer who mentioned feeling more energetic and noticing a more stable heartbeat almost immediately after starting the supplement, suggest that benefits can be felt soon after initiating use Read Review. Others have noted improvements in their overall health and heart function within a few weeks of consistent use, indicating that while immediate effects may occur, significant changes may take a bit longer.
Overall, experiences vary, but testimonials highlight that users often feel notable enhancements in energy levels, reduced fatigue, and improved heart-related symptoms both quickly and progressively over time. Reviewers emphasize the importance of consistency in taking the supplement to achieve optimal benefits, with reports such as feeling rejuvenated and seeing positive health changes suggesting that users begin to notice effects within a matter of days to weeks Read Review. However, it is essential to keep in mind individual health conditions and responses to supplementation may affect these timelines.
Recent research supports the potential of selenium as a beneficial supplement for heart attack recovery. A study involving spherical selenium nanoparticles (SeNPs) demonstrated their ability to reduce heart damage from ischemia/reperfusion injury by disrupting oxidative stress and inflammation cycles, aiding in heart cell protection, and improving heart function post-event [1]. Additionally, another investigation found that selenium, both alone and in combination with pentoxifylline, promoted healing and reduced damage after heart attacks in a rat model, indicating its healing potential [2].
Furthermore, selenium's role as a protective factor was further reinforced by findings linking lower selenium levels to increased heart attack risk among various populations [6]. A collective analysis of these studies suggests that maintaining optimal selenium levels could be crucial for heart health, and while the results are promising, further clinical research is needed to solidify selenium's therapeutic benefits in human subjects following heart attacks. Overall, selenium supplementation presents an intriguing avenue for enhancing recovery after cardiac events, warranting more extensive exploration.
Users have reported a variety of improvements in their symptoms after incorporating selenium supplements into their routines. Many individuals noted enhanced energy levels and reduced fatigue, indicating a significant boost in overall vitality. For instance, one user stated that they experienced a notable increase in energy and stabilized heartbeat almost immediately after starting the supplement Read Review. Another review expressed how the supplement helped alleviate feelings of tiredness and manage heart arrhythmia, characterizing the product as life-changing for their condition Read Review.
Moreover, several users reported improvements in heart health and blood pressure regulation, reinforcing the supplement's reputation for supporting cardiovascular wellness. One review highlighted that the product contributed to better overall health and heart function, elevating physical activity levels Read Review. Other testimonials emphasized the role of selenium in normalizing cholesterol levels and enhancing metabolic functions, ultimately reducing the risk of heart-related issues Read Review. As with any supplement, individual results can vary, and users are encouraged to consider personal health conditions and consult professionals before use.
Users have reported a range of experiences when combining selenium supplements with other health aids for managing heart attack risks and overall heart health. One reviewer emphasized the importance of selenium, highlighting its role in normalizing fat metabolism and cholesterol, which is particularly advantageous for those with arrhythmia and heart disease Read Review. Another user noted that alongside selenium supplementation, they were able to avoid hormone therapy while managing heart issues, suggesting that the supplement provided significant support during their recovery Read Review.
Moreover, several users mentioned that taking selenium contributed positively to their physical health, energy levels, and overall heart function, indicating a synergistic effect when paired with other health strategies. For example, one user found that the supplement played a crucial role in enhancing cardiovascular health and improving blood flow, thereby potentially offering broader benefits when combined with a balanced diet or other heart-supportive supplements Read Review. Overall, while individual results may vary, user experiences suggest that combining selenium with a comprehensive health regimen can bolster heart health and reduce the risk of heart attacks.
Based on user reviews, selenium has been reported as an essential supplement for reducing risks associated with heart attacks and improving overall cardiovascular health. Users confirmed its effectiveness in addressing heart-related issues, with one individual expressing that it has been life-changing for their arrhythmia and fatigue complications Read Review. Many users noted improvements in energy levels and heart function when incorporating selenium into their diets regularly Read Review.
While specific dosing details weren't provided directly by users, the consistent mention of regular consumption of selenium capsules—often taken in the morning before meals—suggests a routine that many found beneficial Read Review. The general consensus appears to advocate for a daily intake of selenium as part of a heart-healthy lifestyle, but users did not specify exact doses. However, its reported role in normalizing fat metabolism and cholesterol stands out, indicating how it serves to protect heart health Read Review.
9
Improved energy levels
4 people found this helpful
The complex is effective! I began taking it on the advice of a nutritionist to restore my thyroid function, addressing fatigue, muscle weakness, and heart issues. Almost immediately, I felt better; my energy increased, hair loss decreased, and my heartbeat was more stable. I recommend this essential vitamin for optimal body performance. Please like if you find this helpful.
9
Improved heart function
1 people found this helpful
Selenium is vital for health; it aids iron and iodine absorption, boosts immunity, and lowers heart attack risks while improving blood pressure. I took it regularly and felt more energetic and rejuvenated. The capsules are easy to take in the morning before meals. Please like if this helped!
9
Avoided hormone therapy
1 people found this helpful
I avoided hormone therapy thanks to this product. I felt constantly tired with heart arrhythmia last year, but this selenium product has been life-changing. I definitely don't want to go without it.
7.5
Enhanced physical activity
1 people found this helpful
I found significant benefits from this supplement. It boosted my physical activity and decreased fatigue due to thyroid issues, contributing to better overall health and heart function.
6
Normalised metabolism
Selenium is essential for those with arrhythmia and heart disease. It normalises fat metabolism and cholesterol, protecting my heart and reducing my risk of heart attack.
7.5
Promotes cardiovascular health
1 people found this helpful
Excellent! Selenium-rich foods enhance cardiovascular health, acting as an anti-inflammatory and improving blood flow. Studies suggest selenium reduces the risk of heart disease and combats atherosclerosis.
7.5
Enhanced cellular immunity
20 people found this helpful
Selenium is crucial for immune function and fat metabolism, lowering heart attack risks while improving blood pressure. I feel more energetic and rejuvenated. I take the capsules in the morning before meals. Please like if this was helpful!
6
Convenient supplement
Selenium is essential for heart disease and recovery post-heart attack. It normalises fat metabolism and cholesterol, protecting my heart. The capsules are small, convenient, and effective.
9
Selenium nanoparticles aid heart recovery
Mitigation of ischemia/reperfusion injury via selenium nanoparticles: Suppression of STAT1 to inhibit cardiomyocyte oxidative stress and inflammation.
We investigated the potential of spherical selenium nanoparticles (SeNPs) to reduce the harmful effects of ischemia/reperfusion injury (I/RI) that often occurs after a heart attack. The study involved intravenous injections of these nanoparticles, which showcased impressive antioxidant and anti-inflammatory properties.
Our findings revealed that SeNPs effectively disrupted the harmful cycle of oxidative stress and inflammation associated with heart damage. They helped protect the heart cells by keeping mitochondrial functions intact and reducing programmed cell death, also known as apoptosis. Furthermore, SeNPs managed to lessen the invasion of inflammatory cells and reduce the release of harmful mediators during I/RI.
In practical terms, when tested in vivo, the selenium nanoparticles significantly improved heart function while reducing both cell death and tissue scarring. This indicates that these nanoparticles could offer a promising new approach to enhance treatments following heart attacks, specifically by focusing on the key pathway of STAT1, which plays a crucial role in mediating injury and inflammation.
8
Selenium enhances heart recovery
Enhancement of cardiac angiogenesis in a myocardial infarction rat model using selenium alone and in combination with PTXF: the role of Akt/HIF-1α signaling pathway.
We explored the effects of selenium (Se) on heart health, specifically its ability to promote healing after a heart attack, also known as myocardial infarction (MI). Our research was conducted using a rat model where we induced heart attacks using a chemical agent called isoprenaline (ISP). After one week, we administered selenium either by itself or combined with another treatment, pentoxifylline (PTXF).
We found that selenium, both alone and with PTXF, showed promising potential in reducing damage caused by heart attacks. The treatment led to improvements in heart function indicators and enhanced angiogenesis, which is the formation of new blood vessels—critical for healing. Importantly, the combination of selenium and PTXF was more effective than using either treatment separately.
Our study highlights the beneficial effects of selenium on cardiac health and suggests a new avenue for treatment strategies following heart attacks. These results point to selenium, especially combined with PTXF, as a potentially impactful option for further investigation in clinical settings.
8
Selenium levels and heart health
Serum Selenium and Incident Cardiovascular Disease in the PREvención con DIeta MEDiterránea (PREDIMED) Trial: Nested Case-Control Study.
A recent case-control study within the PREDIMED trial aimed to find out if low selenium levels might increase the risk of heart attacks and other cardiovascular events. We focused on a group of 207 participants who had experienced significant cardiovascular events, such as heart attacks or strokes, and compared them to 436 controls that matched in sex, age, and intervention group.
The findings revealed that women with a heart condition had lower selenium levels compared to those without, suggesting a possible link between selenium deficiency and heart health. Interestingly, we discovered that, across all participants, there was an inverse relationship between selenium levels and cardiovascular risk. In fact, those with higher selenium concentrations experienced a reduced risk for their first cardiovascular event, highlighting the mineral's potential protective role.
While compared to dietary habits, selenium levels were found to be influenced by factors such as protein and fish intake, as well as age and body mass index. This connection indicates that a well-rounded diet might enhance selenium levels, potentially bolstering heart health.
Ultimately, though we found some positive associations between selenium levels and cardiovascular risk, it’s essential to note the varying factors at play, especially given that lifestyle and diet also play a significant role in cardiovascular health.
References
Chen C, Ma J, Duan S, Xue M, Yang Z, et al. Mitigation of ischemia/reperfusion injury via selenium nanoparticles: Suppression of STAT1 to inhibit cardiomyocyte oxidative stress and inflammation. Biomaterials. 2025;318:123119. 10.1016/j.biomaterials.2025.123119
Elseweidy MM, Ali SI, Shaheen MA, Abdelghafour AM, Hammad SK. Enhancement of cardiac angiogenesis in a myocardial infarction rat model using selenium alone and in combination with PTXF: the role of Akt/HIF-1α signaling pathway. Naunyn Schmiedebergs Arch Pharmacol. 2024;397:4677. 10.1007/s00210-023-02904-9
Sun Q, Yao J, Zhang Z, Li J, Zhang X, et al. Facile fabrication of biocompatible injectable blended polymeric hydrogel with bioactive nanoformulation to improving cardiac tissue regeneration efficiency after myocardial infarction for nursing care potential applications. Nanotoxicology. 2023;17:432. 10.1080/17435390.2023.2252921
Wang Z, Yang N, Hou Y, Li Y, Yin C, et al. L-Arginine-Loaded Gold Nanocages Ameliorate Myocardial Ischemia/Reperfusion Injury by Promoting Nitric Oxide Production and Maintaining Mitochondrial Function. Adv Sci (Weinh). 2023;10:e2302123. 10.1002/advs.202302123
Sun Q, Ma H, Zhang J, You B, Gong X, et al. A Self-Sustaining Antioxidant Strategy for Effective Treatment of Myocardial Infarction. Adv Sci (Weinh). 2023;10:e2204999. 10.1002/advs.202204999
Gutiérrez-Bedmar M, Gil F, Olmedo P, Ruiz-Canela M, Martínez-González MÁ, et al. Serum Selenium and Incident Cardiovascular Disease in the PREvención con DIeta MEDiterránea (PREDIMED) Trial: Nested Case-Control Study. J Clin Med. 2022;11. 10.3390/jcm11226664
Yang C, Zhu C, Li Y, Li Z, Zhang Z, et al. Injectable selenium-containing polymeric hydrogel formulation for effective treatment of myocardial infarction. Front Bioeng Biotechnol. 2022;10:912562. 10.3389/fbioe.2022.912562
Filonenko M, Zhuravlyova L, Sokolnikova N. CORRELATION OF CARDIAC BIOMARKERS WITH THE LEVELS OF SELENIUM AND ANTIOXIDANT ENZYMES IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION AND A HISTORY OF HYPERTENSION. Wiad Lek. 2022;75:362.
Frączek-Jucha M, Kabat M, Szlósarczyk B, Czubek U, Nessler J, et al. Selenium deficiency and the dynamics of changes of thyroid profile in patients with acute myocardial infarction and chronic heart failure. Kardiol Pol. 2019;77:674. 10.33963/KP.14822
Büttner P, Obradovic D, Wunderlich S, Feistritzer HJ, Holzwirth E, et al. Selenoprotein P in Myocardial Infarction With Cardiogenic Shock. Shock. 2020;53:58. 10.1097/SHK.0000000000001342
Khaki-Khatibi F, Mansouri F, Hajahmadipoorrafsanjani M, Ghojazadeh M, Gholikhani-Darbroud R. Study of rs1137101 polymorphism of leptin receptor gene with serum levels of selenium and copper in the patients of non-ST-segment elevation myocardial infarction (NSTEMI) in an Iranian population. Clin Biochem. 2018;60:64. 10.1016/j.clinbiochem.2018.06.016
Dallak M. A synergistic protective effect of selenium and taurine against experimentally induced myocardial infarction in rats. Arch Physiol Biochem. 2017;123:344. 10.1080/13813455.2017.1347687
Hu XF, Eccles KM, Chan HM. High selenium exposure lowers the odds ratios for hypertension, stroke, and myocardial infarction associated with mercury exposure among Inuit in Canada. Environ Int. 2017;102:200. 10.1016/j.envint.2017.03.002
Afridi HI, Kazi TG, Talpur FN, Kazi A, Arain SS, et al. Interaction between selenium and mercury in biological samples of Pakistani myocardial infarction patients at different stages as related to controls. Biol Trace Elem Res. 2014;158:143. 10.1007/s12011-014-9932-8
Li T, Liu X, Yang B, Wang Z, Chen Y, et al. Selenium-loaded porous silica nanospheres improve cardiac repair after myocardial infarction by enhancing antioxidant activity and mitophagy. Free Radic Biol Med. 2025;232:292. 10.1016/j.freeradbiomed.2025.03.004
Al-Rasheed NM, Attia HA, Mohamed RA, Al-Rasheed NM, Al-Amin MA. Preventive effects of selenium yeast, chromium picolinate, zinc sulfate and their combination on oxidative stress, inflammation, impaired angiogenesis and atherogenesis in myocardial infarction in rats. J Pharm Pharm Sci. 2013;16:848.
Siniavskiĭ IuA, Kraĭsman VA, Suleĭmenova ZhM. [Using of a specialized fermented soy milk product on the basis of soybeans in cardiology practice]. Vopr Pitan. 2013;82:51.
Ošt'ádalová I. Biological effects of selenium compounds with a particular attention to the ontogenetic development. Physiol Res. 2012;61:S19.
Zeng Q, Liao M, Li Y, She F, Zhang P. Association between dietary vitamin E intake and incident cardiovascular disease, cardiovascular, and all-cause mortality: A prospective cohort study using NHANES 2003-2018 data. Int J Cardiol Cardiovasc Risk Prev. 2025;24:200340. 10.1016/j.ijcrp.2024.200340
Zhang F, Zhang Y, Qian S, Qian X, Jiao J, et al. Injectable and Conductive Nanomicelle Hydrogel with α-Tocopherol Encapsulation for Enhanced Myocardial Infarction Repair. ACS Nano. 2024;18:10216. 10.1021/acsnano.4c00509
Wang T, Xu L. Circulating Vitamin E Levels and Risk of Coronary Artery Disease and Myocardial Infarction: A Mendelian Randomization Study. Nutrients. 2019;11. 10.3390/nu11092153
Pongkan W, Takatori O, Ni Y, Xu L, Nagata N, et al. β-Cryptoxanthin exerts greater cardioprotective effects on cardiac ischemia-reperfusion injury than astaxanthin by attenuating mitochondrial dysfunction in mice. Mol Nutr Food Res. 2017;61. 10.1002/mnfr.201601077
Loffredo L, Perri L, Di Castelnuovo A, Iacoviello L, De Gaetano G, et al. Supplementation with vitamin E alone is associated with reduced myocardial infarction: a meta-analysis. Nutr Metab Cardiovasc Dis. 2015;25:354. 10.1016/j.numecd.2015.01.008
Shukla SK, Sharma SB, Singh UR. Pre-treatment with α-tocopherol and Terminalia arjuna ameliorates, pro-inflammatory cytokines, cardiac and apoptotic markers in myocardial infracted rats. Redox Rep. 2015;20:49. 10.1179/1351000214Y.0000000104
Rodrigo R, Hasson D, Prieto JC, Dussaillant G, Ramos C, et al. The effectiveness of antioxidant vitamins C and E in reducing myocardial infarct size in patients subjected to percutaneous coronary angioplasty (PREVEC Trial): study protocol for a pilot randomized double-blind controlled trial. Trials. 2014;15:192. 10.1186/1745-6215-15-192
Vardi M, Blum S, Levy AP. Haptoglobin genotype and cardiovascular outcomes in diabetes mellitus - natural history of the disease and the effect of vitamin E treatment. Meta-analysis of the medical literature. Eur J Intern Med. 2012;23:628. 10.1016/j.ejim.2012.04.009
Rautiainen S, Akesson A, Levitan EB, Morgenstern R, Mittleman MA, et al. Multivitamin use and the risk of myocardial infarction: a population-based cohort of Swedish women. Am J Clin Nutr. 2010;92:1251. 10.3945/ajcn.2010.29371
Blum S, Vardi M, Brown JB, Russell A, Milman U, et al. Vitamin E reduces cardiovascular disease in individuals with diabetes mellitus and the haptoglobin 2-2 genotype. Pharmacogenomics. 2010;11:675. 10.2217/pgs.10.17
Punithavathi VR, Prince PS. Pretreatment with a combination of quercetin and alpha-tocopherol ameliorates adenosine triphosphatases and lysosomal enzymes in myocardial infarcted rats. Life Sci. 2010;86:178. 10.1016/j.lfs.2009.11.021